Newswise -- Buying medicine by mail may encourage patients to stick
to their doctor-prescribed medication regimen, new research suggests.
Patients with diabetes, high blood pressure and high cholesterol
Researchers from UCLA and Kaiser
Permanente's Division of Research in Oakland, Calif., found that
patients with diabetes, high blood pressure and high cholesterol who
ordered their medications by mail were more likely to take them as
prescribed by their physicians than patients who obtained medications
from a local pharmacy.
"The
field of medication adherence research typically focuses on patient
factors for poor adherence, leading to a 'blame the patient' approach
for non-adherence," said Dr. O. Kenrik Duru, the study's lead
researcher and an assistant professor in the division of general
internal medicine and health services research at the David Geffen
School of Medicine at UCLA.
Streamline the medication-acquisition process
"Our work helps to place this issue
in a larger perspective," Duru said. "Our findings indicate that
mail-order pharmacies streamline the medication-acquisition process,
which is associated with better medication adherence."
The researchers found
that 84.7 percent of patients who received their medications by mail at
least two-thirds of the time stuck to their physician-prescribed
regimen, compared with 76.9 percent of those who picked up their
medications at traditional "brick-and-mortar" Kaiser Permanente
pharmacies.
"The results were consistent for all three classes of
medication, including medications to control diabetes, high blood
pressure and high cholesterol," said co-investigator Julie A.
Schmittdiel, Ph.D., a research scientist with the Kaiser Permanente
research division.
Other findings include:
• Before
adjusting for other variables, white patients were more likely than
Hispanics to obtain medications by mail (61.0 percent vs. 37.1 percent)
and to be in the highest socioeconomic status quartile (27.5 percent
vs. 17.8 percent).
• Mail-order pharmacy users were more likely
than local pharmacy users to have a financial incentive to fill their
prescriptions (49.6 percent vs. 23.0 percent) and to live a greater
distance from a local pharmacy (8.0 miles vs. 6.7 miles). An example of
a financial incentive is receiving a three-month supply of medication
for the cost of a two-month supply.
• After adjusting for other
variables, whites were more likely to use mail-order pharmacies (24.1
percent) than were Asian/Pacific Islanders (8.4 percent), Hispanics
(5.2 percent), African Americans (4.0 percent) and individuals of mixed
race (8.0 percent).
While other research has examined the
association between medication costs and mail-order and local
pharmacies, this is the first study to look at the relationship between
pharmacy type and medication adherence. Furthermore, it controls for
differences in out-of-pocket costs and medication supply (by number of
days) between mail-order and local pharmacy users, something other
datasets have not included.
"In other words, our study is able
to isolate the use of mail-order pharmacies specifically, without the
results being affected by differences in cost or in the number of pills
provided with each dispensing," Duru said.
The study does have some limitations. For example, the findings need to be confirmed by a randomized controlled trial.
Still, the research suggests that increased mail-order use to obtain medications could improve patients' adherence.
In
addition to Duru and Schmittdiel, researchers included Wendy Dyer,
Melissa Parker, Connie Uratsu, James Chan and Andrew J. Karter of the
research division at Kaiser Permanente Northern California.
Grants
from the U.S. Centers for Disease Control and Prevention and the
National Institute of Diabetes and Digestive and Kidney Diseases funded
this study.
The Kaiser Permanente Division of Research conducts,
publishes and disseminates epidemiologic and health services research
to improve the health and medical care of Kaiser Permanente members and
society at large.
The General Internal Medicine and Health
Services Research Division in the department of medicine at the David
Geffen School of Medicine at UCLA provides a unique interactive
environment for collaborative efforts between health services
researchers and clinical experts with experience in evidence-based
work.